Text on the left with main image on the right. Single row thumbnails on right of main image.
Text - Single column on the left.
Note: Adding thumbnails on the sides, resizes the main image accordingly
This design layout is good if you want to have a lot of text in the work.
With the thumbnails positioned on either the left or right, it makes the main image smaller, which then allows more room for the text.
Consider having thumbnails either above or below the main image.